Photomutagenesis by chlorinated phenothiazine tranquilizers.
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منابع مشابه
Inhibition of cellular atp-hydrolyzing activity by tricyclic antidepressants and phenothiazine tranquilizers.
In a variety of cellular and subcellular preparations, total ATP-hydrolyzing activity was potently inhibited by tricyclic antidepressants (TA) and phenothiazine tranquilizers (PT) . In leukocytes, prein~ubation of the cells with 5 x 10 M TA and 1 x 10M PT resulted in up to 878 and 948 inhibition of the ATPase activity . Among TA, dibenzocycloheptadienes were somewhat more potent inhibitors than...
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Cloud point extraction was successfully applied to the preconcentration of phenothiazine derivatives, such as pericyazine (PC), chlorpromazine (CP) and fluphenazine (FUL), for gas chromatography (GC). Phenothiazine derivatives were separated from surfactants by passing the surfactant-rich phase through a cation exchange column after cloud point extraction, permitting the determination of the ph...
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Three phenothiazine (PTZ) derivatives with varying degrees of sulfur oxidation states were synthesized as strong electron donors. The thioether, sulfoxide and sulfone PTZ-derivatives exhibited irreversible oxidation at 0.19 V, 0.29 V and 0.31 V versus ferrocene, respectively. Each PTZ derivative was emissive with lifetimes of 1.7 ns, 0.5 ns, and 0.5 ns and absolute quantum yields of 0.32, 0.23 ...
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THE benefits to both patient and surgeon followed until either their discharge home, conferred by the use of phenothiazine derivatives in anaesthesia are so great that a report on the routine use of these drugs with pethidine as a sole or main anaesthetic agent for adults in general, uroor to a convalescent or other hospital, or until the end of the third week after operation. The types of oper...
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Depending upon whom you heed and what you read, benzodiazepines are either the safest and most useful anxiety relieving drugs so far discovered, or among the more potentially harmful addictive substances. According to their detractors (Lader, 1978; Marks, 1978) benzodiazepines have become increasingly popular because of medical indiscretions and over vigorous advertising. Drugs are neither inhe...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1979
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.76.1.469